The Doctor's Channel - Allergy & Clinical Immunology

Reducing the Symptoms of Arthritis

2008-05-09T12:20:17-04:00

John D. Kelly, IV, MD, Vice Chairman/Director, Sports Medicine/Orthopaedics, Temple University School of Medicine, discusses simple treatments to reduce the painful symptoms associated with arthritis.

References and Resources
van Vugt RM, Rijken PJ, Rietveld AG, van Vugt AC, Dijkmans BA. Antioxidant intervention in rheumatoid arthritis: results of an open pilot study. Clin Rheumatol. 2008 Jun;27(6):771-5.

Lee H, Lee JY, Kim YJ, et al. Acupuncture for symptom management of rheumatoid arthritis: a pilot study. Clin Rheumatol. 2008 May;27(5):641-5.

Smolen JS, Aletaha D. Activity assessments in rheumatoid arthritis. Curr Opin Rheumatol. 2008 May;20(3):306-13.

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Rheumatoid Arthritis Treatment May Reduce the Risk of Cardiovascular Disease

2008-03-10T15:17:21-04:00

Effective rheumatoid arthritis treatment may reduce the risk of heart attacks, strokes, and cardiovascular disease, according to an international study.

References and Resources
Naranjo A, Sokka T, Descalzo M et al. Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Research & Therapy. 2008; 10:R30.

Views: 2072
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Household Allergens

2008-02-12T17:38:07-05:00

Steven G. Kelsen, MD, FACP, FCCP, Professor of Medicine, Microbiology, and Immunology, Temple University School of Medicine, discusses how one can try to alleviate household allergens.

References and Resources
Kim CW, Hong CS. Allergy to miscellaneous household arthropods. Protein Pept Lett. 2007;14(10):982-91.

Yiin LM, Yu CH, Ashley P, Rhoads G. Cleaning efficacy of high-efficiency particulate air-filtered vacuuming and "dry steam" cleaning on carpet. J Occup Environ Hyg. 2008 Feb;5(2):94-9.

Peters JL, Levy JI, Rogers CA, Burge HA, Spengler JD. Determinants of allergen concentrations in apartments of asthmatic children living in public housing. J Urban Health. 2007 Mar;84(2):185-97.

Steven Kelsen Videos on The Doctor’s Channel:
Asthma Treatment
Atopy Due to Dust Mites

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Atopy Due to Dust Mites

2008-02-11T18:22:01-05:00

Steven G. Kelsen, MD, FACP, FCCP, Professor of Medicine, Microbiology, and Immunology, Temple University School of Medicine, discusses dust mites.

References and Resources
Thomas WR, Heinrich TK, Smith WA, Hales BJ. Pyroglyphid house dust mite allergens. Respirology. 2007 Nov;12. Protein Pept Lett. 2007;14(10):943-53.

van den Bemt L, de Vries MP, Cloosterman S, et al. Influence of house dust mite impermeable covers on health-related quality of life of adult patients with asthma: results of a randomized clinical trial. J Asthma. 2007 Dec;44(10):843-8.

Cingi C, Cakli H, Miman O, et al. Correlation of environmental mite levels and the symptoms of allergic rhinitis regarding the efficacy of preventive education. Allergol Immunopathol (Madr). 2007 Nov;35(6):243-247.

Steven Kelsen Videos on The Doctor’s Channel:
Asthma Treatment
Household Allergens

Views: 1576
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Diagnosing Hereditary Angioedema

2008-02-08T14:40:33-05:00

Paula Busse, MD, Assistant Professor, Medicine and Clinical Immunology, Mount Sinai School of Medicine, discusses how to diagnose hereditary angioedema.

References and Resources
Bernstein JA. Hereditary angioedema: a current state-of-the-art review, VIII: current status of emerging therapies. Dig Dis Sci. 2007 Feb;52(2):353-6Ann Allergy Asthma Immunol. 2008 Jan;100(1 Suppl 2):S41-6

Farkas H, Jakab L, Temesszentandrási G, Visy B, Harmat G, Füst G, Széplaki G, Fekete B, Karádi I, Varga L. Hereditary angioedema: a decade of human C1-inhibitor concentrate therapy. J Allergy Clin Immunol. 2007 Oct;120(4):941-7. Epub 2007 Aug 29.

Lock RJ, Gompels MM. C1-inhibitor deficiencies (hereditary angioedema): where are we with therapies? Curr Allergy Asthma Rep. 2007 Jul;7(4):264-9. Review.

Paula Busse Videos on The Doctor's Channel:
Hereditary Angioedema
TNFα Treatments in Asthma
Asthma in the Elderly

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Clinical Signs of Hereditary Angioedema

2008-01-31T10:08:25-05:00

Paula Busse, MD, Assistant Professor, Medicine and Clinical Immunology, Mount Sinai School of Medicine, discusses the clinical signs and course of hereditary angioedema.

References and Resources
Williams Y, Byrne G, Lynch S, Feighery C, Abuzakouk M. Type II hereditary angioedema: presenting as food allergy. Dig Dis Sci. 2007 Feb;52(2):353-6. Epub 2007 Jan 12. No abstract available.

Janardhanan D, Nair S, Subramanian TS. Recurrent abdominal pain due to hereditary angioedema. Indian J Pediatr. 2007 Jan;74(1):83-4.

Bork K, Meng G, Staubach P, Hardt J. Hereditary angioedema: new findings concerning symptoms, affected organs, and course. Am J Med. 2006 Mar;119(3):267-74.

Paula Busse Videos on The Doctor's Channel:
Hereditary Angioedema
TNFα Treatments in Asthma
Asthma in the Elderly

Views: 655
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Hereditary Angioedema

2008-01-30T16:05:53-05:00

Paula Busse, MD, Assistant Professor, Medicine and Clinical Immunology, Mount Sinai School of Medicine, discusses hereditary angioedema.

References and Resources
Vacca VM Jr. Hereditary angioedema: a case study. J Neurosci Nurs. 2007 Oct;39(5):311-5.

Cicardi M, Zingale LC, Zanichelli A, Deliliers DL, Caccia S. The use of plasma-derived C1 inhibitor in the treatment of hereditary angioedema. JExpert Opin Pharmacother. 2007 Dec;8(18):3173-81.

Bork K, Gül D, Hardt J, Dewald G. Hereditary angioedema with normal C1 inhibitor: clinical symptoms and course. Am J Med. 2007 Nov;120(11):987-92.

Paula Busse Videos on The Doctor's Channel:
Chinese Herbal Treatments for Asthma
TNFα Treatments in Asthma
Asthma in the Elderly

Views: 1500
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Chinese Herbal Treatments for Asthma

2008-01-28T15:29:51-05:00

Paula Busse, MD, Assistant Professor, Medicine and Clinical Immunology, Mount Sinai School of Medicine, discusses the role of Chinese herbal treatments for asthma.

References and Resources
Busse PJ, Wen MC, Huang CK, Srivastava KD, Zhang TF, Schofield B, Sampson HA, Li XM. Therapeutic effects of the Chinese Herbal Formula, MSSM-003d, on persistent airway hyperreactivity and airway remodeling. J Allergy Clin Immunol 2004; 113: S220.

Ko J, Busse PJ, Shek LP, Noone S, Sampson, Li XM. Effect of Chinese herbal formulas on T cell responses in patients with peanut allergy or asthma. J Allergy Clin Immunol 2005; 115:S34.

Zhang TF, Srivastava K, Wen MC, Busse PJ, Qu F, Schofield B, Goldfarb, Kattan M, Sampson H, Dansky H, Li XM. Modulation of Th2 cells and airway smooth muscle cells by ASHMI: a potential asthma treatment (manuscript in preparation).

Paula Busse Videos on The Doctor's Channel:
Hereditary Angioedema
TNFα Treatments in Asthma
Asthma in the Elderly

Views: 769
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TNFα Treatments in Asthma

2008-01-28T15:01:02-05:00

Paula Busse, MD, Assistant Professor, Medicine and Clinical Immunology, Mount Sinai School of Medicine, discusses the role of TNFα treatments in asthma.

References and Resources
Busse PJ, Zhang TF, Srivastava K, Sealfon S, Lin B, Li XM. Chronic administration of tumor necrosis factor alpha increases airway mucus gene expression in vivo. J Allergy Clin Immunol 2005; 116: 1265-63.

Berry M, Brightling C, Pavord I, Wardlaw A. TNF-alpha in asthma. Curr Opin Pharmacol. 2007 Jun;7(3):279-82.

Busse PJ, Fahy JV. In Press. Middleton’s Allergy: Principles and Practices, 7th Edition. Dr. N. Franklin Adkinson Jr editor.

Paula Busse Videos on The Doctor's Channel:
Hereditary Angioedema
Chinese Herbal Treatments for Asthma
Asthma in the Elderly

Views: 634
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Mepolizumab Fails in a Phase II Trial

2007-12-04T15:59:17-05:00

Mepolizumab, an IL-5 inhibitor, failed to alleviate moderate persistent asthma symptoms in a phase II trial of patients resistant to corticosteroids.

References and Resources
Flood-Page P, Swenson C, Faiferman I. A Study to Evaluate Safety and Efficacy of Mepolizumab in Patients with Moderate Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 2007. Vol 176; pp. 1062-1071.

Click Here to view abstract.

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